The Cure Starts Now has funded $18,897,055 in pediatric brain cancer research in partnership with the DIPG / DMG Collaborative. This includes 119 grants at over 100 hospitals in 17 countries.




The Regents of the University of California - $70,000

Amount
$70,000.00
Date

October 2017

An Open Label Single Arm Phase I/II study of MTX110 delivered by convection-enhanced delivery (CED) in patients with diffuse intrinsic pontine glioma (DIPG) previously treated with external beam radiation therapy

The Hospital for Sick Children - $100,560

Amount
$100,560.00
Date

October 2017

MRI Guided Focused Ultrasound: Towards Clinical Translation in Diffuse Intrinsic Pontine Glioma (DIPG)

Texas Children's Hospital and Ann & Robert H. Lurie Children's Hospital of Chicago - $200,000

Amount
$200,000.00
Date

October 2017

Targeting DIPG through Combining a Super-activator (MCB-613) of Steroid Receptor Co-activators with Radiation.

Gustave Roussy - $101,868

Amount
$101,868.00
Date

October 2017

Elucidating the underlying mechanisms of radio resistance at diagnosis and relapse in DIPG

Ospedale Pediatrico Bambino Gesu - $98,987

Amount
$98,987.00
Date

October 2017

Investigating the role of DIPG-derived exosomes in tumor growth and invasion

Memorial Sloan Kettering Cancer Center - $100,000

Amount
$100,000.00
Date

October 2017

Targeting EZH2 as a therapeutic strategy in DIPG

Dana-Farber Cancer Institute - $100,000

Amount
$100,000.00
Date

October 2017

Defining the Cellular Architecture of Diffuse Intrinsic Pontine Glioma through Large-Scale Single-cell RNA-sequencing analyses

The Hospital of Sick Children - $162,828

Amount
$162,828.00
Date

October 2017

Targeting DIPG through pharmacological activation of mitochondrial biogenesis: an in vitro and in vivo preclinical study

Stanford University - $200,000

Amount
$200,000.00
Date

October 2017

Targeting neuronal activity regulated DIPG infiltration

Children's Cancer Institute (AU) - $185,706

Amount
$185,706.00
Date

October 2017

Developing novel combination therapeutic approaches for DIPG targeting Polo-like Kinase 1

Children's National Medical Center - $200,000

Amount
$200,000.00
Date

October 2017

Validation of TAK228 as an effective drug for treating children with DIPG

Ann & Robert H. Lurie Children's Hospital - $100,000

Amount
$100,000.00
Date

October 2017

Determine the efficacy of BMP and MEK inhibitors with RT to treat ACVR1 mutant DIPG

Anschutz Medical Campus - $50,000

Amount
$50,000.00
Date

September 2017

Toward a Multimodality Cure for DIPG: Investigation of Intratumoral Drug Penetration and Craniospinal Irradiation.

Massachusetts General Hospital - $50,000

Amount
$50,000.00
Date

September 2017

Repurposing Mefloquine for Diffuse Intrinsic Pontine Glioma Therapy

CONNECT Consortium - $899,518.80

Amount
$899,518.00
Date

September 2017

CONNECT (COllaborative Network for NEurooncology Clinical Trials) Consortium