Research And Grants

Multiomic Characterization of Central Nervous System Tumors Using Whole Methylome and Comprehensive High-Depth DNAseq and RNAseq to Assess Impact on Historical Patient Diagnoses and Outcomes

Brain tumors are the most common type of solid cancer and the leading cause of cancer-related deaths in children. Recent updates in how these tumors are classified now focus more on genetic testing to unravel the underlying molecular biology, which can change how doctors assess risk, predict outcomes, and provide appropriate personalized management. Our project will use advanced genetic testing (DNA and RNA sequencing and methylation) on stored tumor samples to see if new testing methods might change previous diagnoses or provide new insights based on the latest guidelines from the World Health Organization.